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The BTK-inhibitor ibrutinib may protect against pulmonary injury in COVID-19 infected patients

Descarga: The BTK-inhibitor ibrutinib may protect against pulmonary injury in COVID-19 infected patients Archivo: covid-19/The BTK-inhibitor ibrutinib may protect against pulmonary injury in COVID-19 infected patients. BLOOD.pdf The BTK-inhibitor ibrutinib is used to treat indolent B-cell malignancies and chronic graft versus host disease. The potential for ibrutinib to abrogate pulmonary inflammatory cytokines, lung injury and…

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Thrombosis: a major contributor to the global disease burden

Descarga: Thrombosis: a major contributor to the global disease burden Archivo: ISTH Steering Committee for World Thrombosis Day- Thrombosis a major contributor to the global disease burden 1.pdf ISTH Steering Committee for World Thrombosis Day. Thrombosis: a major contributor to the global disease burden. J Thromb Haemost 2014; 12: 1580–90. Summary. Thrombosis is a common…

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The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro

Descarga: The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro Archivo: covid-19/The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro.pdf Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report here that Ivermectin, an FDA-approved anti-parasitic previously…

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Thrombosis management in times of COVID-19 epidemy; a Dutch perspective

Descarga: Thrombosis management in times of COVID-19 epidemy; a Dutch perspective Archivo: covid-19/Hugo ten Cate- Thrombosis management in times of COVID-19 epidemy_ a Dutch perspective Thrombosis Journal.pdf 1. ten Cate H. Thrombosis management in times of COVID-19 epidemy; a Dutch perspective. Thrombosis Journal. 2020;18(1). The current pandemic of COVID-19 infection [1] has caused major shifts…

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Remdesivir for the Treatment of Covid-19 — Preliminary Report

Descarga: Remdesivir for the Treatment of Covid-19 — Preliminary Report Archivo: covid-19/Remdesivir for the Treatment of Covid-19 05 22 2020.pdf 2. Beigel J, Tomashek K, Dodd L, Mehta A, Zingman B, Kalil A et al. Remdesivir for the Treatment of Covid-19 — Preliminary Report. New England Journal of Medicine. 2020;. BACKGROUNDAlthough several therapeutic agents have…

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Factor VIII inhibitors in hemophilia A: rationale and latest evidence

Descarga: Factor VIII inhibitors in hemophilia A: rationale and latest evidence Archivo: covidhemo/FVIII inhibitors in Hem A rationale and evidence by GY.pdf Abstract: Factor VIII (FVIII) replacement therapy is the foundation of treatment in hemophilia A and is effective unless a patient develops an alloantibody (inhibitor) against exogenous FVIII. Inhibitor development is currently the most…

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Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics

Descarga: Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics Archivo: covid-19/The Lancet Respirattory-Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics.pdf In December, 2019, numerous unexplained pneumonia cases occurred in Wuhan, China. This outbreak was confirmed to be caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2),…

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Definitions in hemophilia: communication from the SSC of the ISTH

Descargar PDF — Definitions in hemophilia: communication from the SSC of the ISTH For the documentation and comparison of outcomes of clinical care in hemophilia, especially with different treatment protocols, as well as in clinical trials of new clotting factor concentrates, it is necessary to have clear definitions of disease-related variables as well as the…

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Compassionate Use of Remdesivir for Patients with Severe Covid-19

Descarga: Compassionate Use of Remdesivir for Patients with Severe Covid-19 Archivo: covid-19/nejmoa- Compassionate Use of Remdesivir- J Grein.pdf BACKGROUNDRemdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases, has shown in vitro activity against SARS-CoV-2. METHODSWe provided remdesivir on a compassionate-use basis to patients hospitalized with Covid-19, the illness caused by infection with SARS-CoV-2. Patients…

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Immune Thrombocytopenic Purpura in a Patient with Covid-19

Descargar PDF — Immune Thrombocytopenic Purpura in a Patient with Covid-19 To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case reports should be viewed as observations rather than as recommendations for evaluation or treatment….

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