Descarga: A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Archivo: covid-19/MILITARY MEDICAL RESEARCH A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus infected pneumonia standard version.pdf AbstractIn December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and…

Descarga: Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 Archivo: covid-19/nejm- Renin Angiotensin Aldosterone System Inhibitors in Patients with Covid 19.pdf The renin–angiotensin–aldosterone system (RAAS) is an elegant cascade of vasoactive peptides that orchestrate key processes in human physiology. Severe acute respiratory syndrome coronavirus 1(SARS-CoV-1) and SARS-CoV-2, which have been responsible for the SARS epidemic in…

Descarga: Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Archivo: covid-19/NATURE- Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.pdf Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells1,2.  Here we identify a metallopeptidase, angiotensin-converting…

Descarga: Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Archivo: covid-19/Drug Dev Res- Angiotensinreceptorblockersastentative SARS-CoV-2therapeutics.pdf AbstractAt the time of writing this commentary (February 2020), the coronavirus COVID-19 epidemic has already resulted in more fatalities compared with the SARS and MERS coronavirus epidemics combined. Therapeutics that may assist to contain its rapid spread and reduce its high mortality rates are…

Descarga: Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID‑19) Archivo: covid-19/Intensive Care Med ICU Surviving Sepsis Campaign guidelines onthe management ofcritically ill adults withCoronavirus Disease 2019.pdf Abstract Background: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease…

Descarga: The past and future of haemophilia: diagnosis, treatments, and its complications Archivo: covidhemo/hemophilia young lancet2562.pdf Haemophilia A and B are hereditary haemorrhagic disorders characterised by defi ciency or dysfunction of coagulation protein factors VIII and IX, respectively. Recurrent joint and muscle bleeds lead to severe and progressive musculoskeletal damage. Existing treatment relies on replacement…

Descarga: Angiotensin‑converting enzyme 2 (ACE2) as a SARS‑CoV‑2 receptor: molecular mechanisms and potential therapeutic target Archivo: covid-19/Intensive Care Med Angiotensin converting enzyme 2 ACE2 asa SARS CoV 2 receptor molecular mechanisms andpotential therapeutic target.pdf A novel infectious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in Wuhan, China, in December 2019. The…

Descarga: Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 Archivo: covid-19/International Journal of Antimicrobial Agents- Journal PRE- Proof Chloroquine-and-hydroxychloroquine-f.pdf Repositioning of drugs for use as antiviral treatments is a critical need [1]. It is commonly very badly perceived by virologists, as we experienced when reporting the effectiveness of azithromycin for Zika virus [2]. A…

Descarga: The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status Archivo: covid-19/Military Medical Research The origin transmission and clinical therapies on coronavirus disease 2019 outbreak an update on the status.pdf AbstractAn acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus…