Categoría: Biblioteca

Descargar PDF — Management of anticoagulation for cancer-associated thrombosis in patients wi… Background: The management of anticoagulation for cancer-associated thrombosis (CAT) in patients with thrombocytopenia is controversial. Whereas some studies suggest that administration of reduced-dose low-molecular-weight heparin (LMWH) or temporary discontinuation for moderate and severe thrombocytopenia may be a safe and effective, others suggest full-dose…

Descarga: Laboratory Testing in the Era of Direct or Non – Vitamin K Antagonist Oral Anticoagulants: A Practical Guide to Measuring Their Activity and Avoiding Diagnostic Errors Archivo: tromboembolia-venosa/STHem 2015 Favaloro lab and DOA.pdf A new generation of antithrombotic agents has recently emerged. These provide direct inhibition of either thrombin (factor IIa [FIIa]) or FXa,…

Descarga: Anticoagulant Effects of Dabigatran in Paediatric Patients Compared with Adults: Combined Data from Three Paediatric Clinical Trials Archivo: tromboembolia-venosa/infancia/th_2016-Age dependency for coagulation parameters in paediatric populations .pdf Background Physiological age-related changes in the haemostatic and coagulation systems result in differing anticoagulant assay responses to standard anticoagulants. Therefore, we investigated the response of anticoagulant assays…

Descarga: Quantification of Platelet Contractile Movements during Thrombus Formation Archivo: tromboembolia-venosa/TH set 2018 quantification of.pdf Imaging methods based on time-lapse micro scopy are important tools for studying the dynamic events that shape thrombus formation upon vascular injury. However, there is a lack of methods to translate the vast amount of visual data generated in such…

Descargar PDF — Apixaban to Prevent Venous Thromboembolism in Patients with Cancer BACKGROUNDPatients with active cancer have an increased risk of venous thromboembolism, which results in substantial morbidity, mortality, and health care expenditures. The Khorana score (range, 0 to 6, with higher scores indicating a higher risk of venous thromboembolism) has been validated to identify…

Descarga: STATE OF THE ART ISTH2017 BERLIN Anticoagulant prophylaxis and therapy in children: current challenges and emerging issues Archivo: tromboembolia-venosa/infancia/jth 2018 anticoag children.pdf Summary.This review is aimed at describing the unique challenges of anticoagulant prophylaxis and treatment in children, and highlighting areas for research for improving clinical outcomes of children with thromboembolic disease. The evidence…

Descarga: Thrombosis as an intravascular effector of innate immunity Archivo: tromboembolia-venosa/engelmann2012 inmunotrombosis.pdf Abstract | Thrombosis is the most frequent cause of mortality worldwide and is closely linked to haemostasis, which is the biological mechanism that stops bleeding after the injury of blood vessels. Indeed, both processes share the core pathways of blood coagulation and platelet…

Descarga: An update on factor XI structure and function Archivo: tromboembolia-venosa/tvp/Thr Res 2018 Mohamed-FXI.pdf Factor XI (FXI) is the zymogen of a plasma protease, factor XIa (FXIa), that contributes to thrombin generation during blood coagulation by proteolytic activation of several coagulation factors, most notably factor IX (FIX). FXI is a homolog of prekallikrein (PK), a…