Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy

Descarga: Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy Archivo: covid-19/Venous and arterial thromboembolic complications in COVID-19 patients admitted toStefano Barco TEV COVID profilaxis en casa 2.pdf Background: Few data are available on the rate and characteristics of thromboembolic complications in hospitalized patients with COVID-19. Methods: We…

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Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol

Descarga: Pharmacogenetic Variation in Over 100 Genes in Patients Receiving Acenocumarol Archivo: tromboembolia-venosa/tvp/POLIMORFISMOS ACO.pdf Coumarins are widely prescribed worldwide, and inMexico acenocumarol is the preferred form. It is well known that despite its efficacy, coumarins show a high variability for dose requirements. We investigated the pharmacogenetic variation of 110 genes in patients receiving acenocumarol using…

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Anticoagulant Effects of Dabigatran in Paediatric Patients Compared with Adults: Combined Data from Three Paediatric Clinical Trials

Descarga: Anticoagulant Effects of Dabigatran in Paediatric Patients Compared with Adults: Combined Data from Three Paediatric Clinical Trials Archivo: tromboembolia-venosa/infancia/th_2016-Age dependency for coagulation parameters in paediatric populations .pdf Background Physiological age-related changes in the haemostatic and coagulation systems result in differing anticoagulant assay responses to standard anticoagulants. Therefore, we investigated the response of anticoagulant assays…

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Quantification of Platelet Contractile Movements during Thrombus Formation

Descarga: Quantification of Platelet Contractile Movements during Thrombus Formation Archivo: tromboembolia-venosa/TH set 2018 quantification of.pdf Imaging methods based on time-lapse micro scopy are important tools for studying the dynamic events that shape thrombus formation upon vascular injury. However, there is a lack of methods to translate the vast amount of visual data generated in such…

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Apixaban to Prevent Venous Thromboembolism in Patients with Cancer

Descargar PDF — Apixaban to Prevent Venous Thromboembolism in Patients with Cancer BACKGROUNDPatients with active cancer have an increased risk of venous thromboembolism, which results in substantial morbidity, mortality, and health care expenditures. The Khorana score (range, 0 to 6, with higher scores indicating a higher risk of venous thromboembolism) has been validated to identify…

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STATE OF THE ART ISTH2017 BERLIN Anticoagulant prophylaxis and therapy in children: current challenges and emerging issues

Descarga: STATE OF THE ART ISTH2017 BERLIN Anticoagulant prophylaxis and therapy in children: current challenges and emerging issues Archivo: tromboembolia-venosa/infancia/jth 2018 anticoag children.pdf Summary.This review is aimed at describing the unique challenges of anticoagulant prophylaxis and treatment in children, and highlighting areas for research for improving clinical outcomes of children with thromboembolic disease. The evidence…

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Thrombosis as an intravascular effector of innate immunity

Descarga: Thrombosis as an intravascular effector of innate immunity Archivo: tromboembolia-venosa/engelmann2012 inmunotrombosis.pdf Abstract | Thrombosis is the most frequent cause of mortality worldwide and is closely linked to haemostasis, which is the biological mechanism that stops bleeding after the injury of blood vessels. Indeed, both processes share the core pathways of blood coagulation and platelet…

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An update on factor XI structure and function

Descarga: An update on factor XI structure and function Archivo: tromboembolia-venosa/tvp/Thr Res 2018 Mohamed-FXI.pdf Factor XI (FXI) is the zymogen of a plasma protease, factor XIa (FXIa), that contributes to thrombin generation during blood coagulation by proteolytic activation of several coagulation factors, most notably factor IX (FIX). FXI is a homolog of prekallikrein (PK), a…

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Increasing rates of thrombosis in children with congenital heart disease undergoing cardiac surgery

Descarga: Increasing rates of thrombosis in children with congenital heart disease undergoing cardiac surgery Archivo: tromboembolia-venosa/infancia/Thr Res 2018 increasing rates of thrombosis in children with.pdf Objective: To determine thrombosis incidence, morbidities, and mortality of children with congenital heart disease who develop thrombosis after cardiac surgery. Materials and methods: This retrospective study reviewed patients< 18 years…

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Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)

Descarga: Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs) Archivo: tromboembolia-venosa/Thr Res 2018 Grasso-FSAP y neutrofilos.pdf The circulating zymogen form of Factor VII activating protease (FSAP) can be activated by histones and nucleosomes in vivo. These cell-death-associated nuclear factors are also actively extruded into the extracellular space by neutrophils through a…

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