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Increasing rates of thrombosis in children with congenital heart disease undergoing cardiac surgery

Descarga: Increasing rates of thrombosis in children with congenital heart disease undergoing cardiac surgery Archivo: tromboembolia-venosa/infancia/Thr Res 2018 increasing rates of thrombosis in children with.pdf Objective: To determine thrombosis incidence, morbidities, and mortality of children with congenital heart disease who develop thrombosis after cardiac surgery. Materials and methods: This retrospective study reviewed patients< 18 years…

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Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)

Descarga: Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs) Archivo: tromboembolia-venosa/Thr Res 2018 Grasso-FSAP y neutrofilos.pdf The circulating zymogen form of Factor VII activating protease (FSAP) can be activated by histones and nucleosomes in vivo. These cell-death-associated nuclear factors are also actively extruded into the extracellular space by neutrophils through a…

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Laboratory Testing in the Era of Direct or Non – Vitamin K Antagonist Oral Anticoagulants: A Practical Guide to Measuring Their Activity and Avoiding Diagnostic Errors

Descarga: Laboratory Testing in the Era of Direct or Non – Vitamin K Antagonist Oral Anticoagulants: A Practical Guide to Measuring Their Activity and Avoiding Diagnostic Errors Archivo: tromboembolia-venosa/STHem 2015 Favaloro lab and DOA.pdf A new generation of antithrombotic agents has recently emerged. These provide direct inhibition of either thrombin (factor IIa [FIIa]) or FXa,…

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French clinical practice guidelines on the management of patients on vitamin K antagonists in at-risk situations (overdose, risk of bleeding, and active bleeding)

Descargar PDF — French clinical practice guidelines on the management of patients on vitamin … The present report from several French medical societies in the field and the French National Authority for Health provides an expert consensus for the management of patients on vitamin K antagonists in at-risk situations (overdose, risk of bleeding, and active…

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Diagnosis of deep vein thrombosis recurrence: Ultrasound criteria

Descarga: Diagnosis of deep vein thrombosis recurrence: Ultrasound criteria Archivo: tromboembolia-venosa/Thr Res 2018 Maufus TVP diagnostico.pdf Introduction: Recurrent deep vein thrombosis (DVT) is often suspected in patients after anticoagulant drug withdrawal. The clinical signs can be confused with the onset of post-thrombotic syndrome. For these reasons, diagnosis of DVT recurrence must rely on an accurate…

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Recombinant FXIII (rFXIII-A 2 ) Prophylaxis Prevents Bleeding and Allows for Surgery in Patients with Congenital FXIII A-Subunit Deficiency

Descarga: Recombinant FXIII (rFXIII-A 2 ) Prophylaxis Prevents Bleeding and Allows for Surgery in Patients with Congenital FXIII A-Subunit Deficiency Archivo: ehh/T Hemost 2018 Carcao recombinant FXIII.pdf Recombinant factor XIII-A 2 (rFXIII-A 2 ) was developed for prophylaxis and treatment of bleeds in patients with congenital FXIII A-subunit de fi ciency. mentor ™ 2 (NCT00978380),…

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An update on factor XI structure and function

Descarga: An update on factor XI structure and function Archivo: tromboembolia-venosa/tvp/Thr Res 2018 Mohamed-FXI.pdf Factor XI (FXI) is the zymogen of a plasma protease, factor XIa (FXIa), that contributes to thrombin generation during blood coagulation by proteolytic activation of several coagulation factors, most notably factor IX (FIX). FXI is a homolog of prekallikrein (PK), a…

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IgA anti-β2 glycoprotein I antibodies: Experience from a large center

Descarga: IgA anti-β2 glycoprotein I antibodies: Experience from a large center Archivo: tromboembolia-venosa/Thr Res IgA and b2-glycoprotein Ab.pdf Objective: IgG and IgM antibodies directed at β2-glycoprotein I are included in the classification criteria for the antiphospholipid syndrome (APS) while the IgA antibodies against β2-glycoprotein I (IgA aβ2GPI) are not.Conflicting data about the significance of IgA…

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STATE OF THE ART ISTH2017 BERLIN Anticoagulant prophylaxis and therapy in children: current challenges and emerging issues

Descarga: STATE OF THE ART ISTH2017 BERLIN Anticoagulant prophylaxis and therapy in children: current challenges and emerging issues Archivo: tromboembolia-venosa/infancia/jth 2018 anticoag children.pdf Summary.This review is aimed at describing the unique challenges of anticoagulant prophylaxis and treatment in children, and highlighting areas for research for improving clinical outcomes of children with thromboembolic disease. The evidence…

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Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant

Descargar PDF — Perioperative Management of Patients With Atrial Fibrillation Receiving a Dir… IMPORTANCE Patients with atrial fibrillation (AF) who use a direct oral anticoagulant (DOAC) and request elective surgery or procedure present a common clinical situation yet perioperative management is uncertain. OBJECTIVE To investigate the safety of a standardized perioperative DOAC managementstrategy. DESIGN, SETTING,…

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