Categoría: Tromboembolia Arterial

Descarga: Effect of Clopidogrel on Platelet Aggregation and Plasma Concentration of Fibrinogen in Subjects with Cerebral or Coronary Atherosclerotic Disease Archivo: tromboembolia-arterial/Izaguirre.CPGRL.Clin Appl Throm Hemost.pdf Summary: Acetylsalicylic acid inhibits thromboxane A2 production and reduces the risk of vascular occlusive events by 20% to 25%. Ticlopidine inhibits ADP-dependent platelet aggregation and reduces the same risk by…

Descarga: Antiplatelet effect of aspirin during 24 h in patients with type 2 diabetes without cardiovascular disease Archivo: tromboembolia-arterial/cardiopatia/Thr Res 2018 Vernstrom-asp y diabetes.pdf Introduction: The antiplatelet effect of low-dose aspirin in patients with type 2 diabetes (T2DM) without cardiovascular disease (CVD) has not been thoroughly explored. We investigated if  platelet aggregation increased during the…

Descargar PDF — Perioperative Management of Patients With Atrial Fibrillation Receiving a Dir… IMPORTANCE Patients with atrial fibrillation (AF) who use a direct oral anticoagulant (DOAC) and request elective surgery or procedure present a common clinical situation yet perioperative management is uncertain. OBJECTIVE To investigate the safety of a standardized perioperative DOAC managementstrategy. DESIGN, SETTING,…

Descargar PDF — Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source BACKGROUND Embolic strokes of undetermined source represent 20% of ischemic strokes and are associated with a high rate of recurrence. Anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, may result in a lower risk of recurrent stroke than aspirin.METHODS We compared…

Descargar PDF — Move along, nothing to see here: Btk inhibitors stop platelets sticking to pl… Platelets have evolved an intricate array of overlapping mechanisms to respond effectively to vessel damage by forming a clot to minimize blood loss. Unfortunately, these same responses may also be triggered by atherosclerotic lesions in diseased arteries. Vessels can…

Descargar PDF — Antiplatelet and Anticoagulant Therapies for Prevention of Ischemic Stroke Ischemic stroke represents one of the leading causes of death and disability in both the United States and abroad, particularly for patients with prior ischemic stroke or transient ischemic attack (TIA). A quintessential aspect of secondary stroke prevention is the use of different…

Descargar PDF — Trombocitopenia Inducida por Heparina (HIT) Trombocitopenia Inducida por Heparina (HIT)Marta E MartinuzzoFundación Favaloro. Hospital Universitario. Buenos Aires, ArgentinaDefiniciónEs una reacción adversa del tratamiento con heparinas, es de origen inmunológico, se produce por la generación de anticuerpos dirigidos contra el complejo formado por el factor plaquetario 4 (PF4) y la heparina (Hep), que…