Categoría: Phoca Downloads Import

Descarga: Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Archivo: covid-19/NATURE- Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.pdf Spike (S) proteins of coronaviruses, including the coronavirus that causes severe acute respiratory syndrome (SARS), associate with cellular receptors to mediate infection of their target cells1,2.  Here we identify a metallopeptidase, angiotensin-converting…

Descarga: A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 Archivo: covid-19/nejm A Trial of Lopinavir Ritonavir in Adults Hospitalized with Severe Covid 19.pdf BACKGROUNDNo therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. METHODSWe conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2…

Descarga: Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 Archivo: covid-19/nejm- Renin Angiotensin Aldosterone System Inhibitors in Patients with Covid 19.pdf The renin–angiotensin–aldosterone system (RAAS) is an elegant cascade of vasoactive peptides that orchestrate key processes in human physiology. Severe acute respiratory syndrome coronavirus 1(SARS-CoV-1) and SARS-CoV-2, which have been responsible for the SARS epidemic in…

Descarga: Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics Archivo: covid-19/The Lancet Respirattory-Therapeutic and triage strategies for 2019 novel coronavirus disease in fever clinics.pdf In December, 2019, numerous unexplained pneumonia cases occurred in Wuhan, China. This outbreak was confirmed to be caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2),…

Descargar PDF — Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19 To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case reports should be viewed as observations rather than as recommendations for evaluation or treatment….

Descarga: Compassionate Use of Remdesivir for Patients with Severe Covid-19 Archivo: covid-19/nejmoa- Compassionate Use of Remdesivir- J Grein.pdf BACKGROUNDRemdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases, has shown in vitro activity against SARS-CoV-2. METHODSWe provided remdesivir on a compassionate-use basis to patients hospitalized with Covid-19, the illness caused by infection with SARS-CoV-2. Patients…

Descargar PDF — Immune Thrombocytopenic Purpura in a Patient with Covid-19 To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case reports should be viewed as observations rather than as recommendations for evaluation or treatment….

Descarga: COVID-19: combining antiviral and anti-inflammatory treatments Archivo: covid-19/COVID19 combining antiviral and anti inflammatory.pdf Both coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) are characterised by an overexuberant inflammatory response and, for SARS, viral load is not correlated with the worsening of symptoms.1,2 In our previous Correspondence to The Lancet,3 we described how BenevolentAI’s proprietary artificial intelligence (AI)-derived knowledge  graph,4…

Descarga: Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Archivo: covid-19/Drug Dev Res- Angiotensinreceptorblockersastentative SARS-CoV-2therapeutics.pdf AbstractAt the time of writing this commentary (February 2020), the coronavirus COVID-19 epidemic has already resulted in more fatalities compared with the SARS and MERS coronavirus epidemics combined. Therapeutics that may assist to contain its rapid spread and reduce its high mortality rates are…