COVID-19: combining antiviral and anti-inflammatory treatments

Descarga: COVID-19: combining antiviral and anti-inflammatory treatments Archivo: covid-19/COVID19 combining antiviral and anti inflammatory.pdf Both coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) are characterised by an overexuberant inflammatory response and, for SARS, viral load is not correlated with the worsening of symptoms.1,2 In our previous Correspondence to The Lancet,3 we described how BenevolentAI’s proprietary artificial intelligence (AI)-derived knowledge  graph,4…

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Definitions in hemophilia: communication from the SSC of the ISTH

Descargar PDF — Definitions in hemophilia: communication from the SSC of the ISTH For the documentation and comparison of outcomes of clinical care in hemophilia, especially with different treatment protocols, as well as in clinical trials of new clotting factor concentrates, it is necessary to have clear definitions of disease-related variables as well as the…

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Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics

Descarga: Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Archivo: covid-19/Drug Dev Res- Angiotensinreceptorblockersastentative SARS-CoV-2therapeutics.pdf AbstractAt the time of writing this commentary (February 2020), the coronavirus COVID-19 epidemic has already resulted in more fatalities compared with the SARS and MERS coronavirus epidemics combined. Therapeutics that may assist to contain its rapid spread and reduce its high mortality rates are…

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Factor VIII inhibitors in hemophilia A: rationale and latest evidence

Descarga: Factor VIII inhibitors in hemophilia A: rationale and latest evidence Archivo: covidhemo/FVIII inhibitors in Hem A rationale and evidence by GY.pdf Abstract: Factor VIII (FVIII) replacement therapy is the foundation of treatment in hemophilia A and is effective unless a patient develops an alloantibody (inhibitor) against exogenous FVIII. Inhibitor development is currently the most…

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Angiotensin‑converting enzyme 2 (ACE2) as a SARS‑CoV‑2 receptor: molecular mechanisms and potential therapeutic target

Descarga: Angiotensin‑converting enzyme 2 (ACE2) as a SARS‑CoV‑2 receptor: molecular mechanisms and potential therapeutic target Archivo: covid-19/Intensive Care Med Angiotensin converting enzyme 2 ACE2 asa SARS CoV 2 receptor molecular mechanisms andpotential therapeutic target.pdf A novel infectious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in Wuhan, China, in December 2019. The…

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The past and future of haemophilia: diagnosis, treatments, and its complications

Descarga: The past and future of haemophilia: diagnosis, treatments, and its complications Archivo: covidhemo/hemophilia young lancet2562.pdf Haemophilia A and B are hereditary haemorrhagic disorders characterised by defi ciency or dysfunction of coagulation protein factors VIII and IX, respectively. Recurrent joint and muscle bleeds lead to severe and progressive musculoskeletal damage. Existing treatment relies on replacement…

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Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID‑19)

Descarga: Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID‑19) Archivo: covid-19/Intensive Care Med ICU Surviving Sepsis Campaign guidelines onthe management ofcritically ill adults withCoronavirus Disease 2019.pdf Abstract Background: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease…

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The COVID-19 Pandemic: New Global Challenges for the Hemophilia Community

Descargar PDF — The COVID-19 Pandemic: New Global Challenges for the Hemophilia Community Over the past few decades, several blood-borne viruses have targeted hemophilia patients requiring treatment with clotting factors derived from human plasma [1]. Even today, many hemophilia patients and their families still retain painful and indelible memories of HIV and hepatitis C infections…

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Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Descarga: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Archivo: covid-19/Intensive Care Medicine Surviving Sepsis Campaign Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019.pdf AbstractBackgroundThe novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019…

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Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy

Descarga: Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy Archivo: covid-19/Venous and arterial thromboembolic complications in COVID-19 patients admitted toStefano Barco TEV COVID profilaxis en casa 2.pdf Background: Few data are available on the rate and characteristics of thromboembolic complications in hospitalized patients with COVID-19. Methods: We…

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