Categoría: Phoca Downloads Import

Descarga: Compassionate Use of Remdesivir for Patients with Severe Covid-19 Archivo: covid-19/nejmoa- Compassionate Use of Remdesivir- J Grein.pdf BACKGROUNDRemdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases, has shown in vitro activity against SARS-CoV-2. METHODSWe provided remdesivir on a compassionate-use basis to patients hospitalized with Covid-19, the illness caused by infection with SARS-CoV-2. Patients…

Descargar PDF — Immune Thrombocytopenic Purpura in a Patient with Covid-19 To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case reports should be viewed as observations rather than as recommendations for evaluation or treatment….

Descarga: COVID-19: combining antiviral and anti-inflammatory treatments Archivo: covid-19/COVID19 combining antiviral and anti inflammatory.pdf Both coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome (SARS) are characterised by an overexuberant inflammatory response and, for SARS, viral load is not correlated with the worsening of symptoms.1,2 In our previous Correspondence to The Lancet,3 we described how BenevolentAI’s proprietary artificial intelligence (AI)-derived knowledge  graph,4…

Descarga: Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Archivo: covid-19/Drug Dev Res- Angiotensinreceptorblockersastentative SARS-CoV-2therapeutics.pdf AbstractAt the time of writing this commentary (February 2020), the coronavirus COVID-19 epidemic has already resulted in more fatalities compared with the SARS and MERS coronavirus epidemics combined. Therapeutics that may assist to contain its rapid spread and reduce its high mortality rates are…

Descarga: Factor VIII inhibitors in hemophilia A: rationale and latest evidence Archivo: covidhemo/FVIII inhibitors in Hem A rationale and evidence by GY.pdf Abstract: Factor VIII (FVIII) replacement therapy is the foundation of treatment in hemophilia A and is effective unless a patient develops an alloantibody (inhibitor) against exogenous FVIII. Inhibitor development is currently the most…

Descarga: Angiotensin‑converting enzyme 2 (ACE2) as a SARS‑CoV‑2 receptor: molecular mechanisms and potential therapeutic target Archivo: covid-19/Intensive Care Med Angiotensin converting enzyme 2 ACE2 asa SARS CoV 2 receptor molecular mechanisms andpotential therapeutic target.pdf A novel infectious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in Wuhan, China, in December 2019. The…

Descarga: The past and future of haemophilia: diagnosis, treatments, and its complications Archivo: covidhemo/hemophilia young lancet2562.pdf Haemophilia A and B are hereditary haemorrhagic disorders characterised by defi ciency or dysfunction of coagulation protein factors VIII and IX, respectively. Recurrent joint and muscle bleeds lead to severe and progressive musculoskeletal damage. Existing treatment relies on replacement…

Descarga: Managing COVID-19 in Low- and Middle-Income Countries Archivo: covid-19/JAMA Managing COVID -19 in low -and middle -income countries- J Hopman.pdf Thepublic health response to coronavirus disease 2019 (COVID-19) in China has illustrated that it is possible to contain COVID-19 if governments focus on tried and tested public health outbreak responses.1,2 Isolation, quarantine, social distancing,…

Descarga: Undocumented U.S. Immigrants and Covid-19 Archivo: covid-19/nejm-Undocumente U.S. Immigrants and COVID-19 Kathleen R.pdf In 2019, as the “public charge” rule made its way through the U.S. court system, many low income immigrant parents of American children in the Johns Hopkins pediatric practice asked our case managers to disenroll their children from the Supplemental Nutrition…