Descarga: Cancer-associated venous thromboembolism: Burden, mechanisms, and management Archivo: tromboembolia-venosa/tvp/th_2017-Cancer-associated venous thromboembolism.pdf Venous thromboembolism (VTE) is a significant health problem in the general population but especially in cancer patients. In this review, we discuss the epidemiology and burden of the disease, the pathophysiology of cancer-associated VTE, and the clinical treatment options for both primary prevention…

Descarga: Role of monocytes and endothelial cells in heparin-induced thrombocytopenia Archivo: tromboembolia-venosa/tvp/th_2016-Role of monocytes and endothelial cells in heparin-induced thrombocytopenia.pdf Heparin-induced thrombocytopenia (HIT) is an autoimmune disorder characterised by thrombocytopenia and thrombosis. The mechanisms leading to platelet destruction are complex and the thrombotic complications of HIT appear to be due to multiple different intravascular targets….

Descarga: Management of the multiple phases of heparin-induced thrombocytopenia Archivo: tromboembolia-venosa/tvp/th_2016-Management of the multiple phases of heparin-induced thrombocytopenia.pdf The clinical course of heparin-induced thrombocytopenia (HIT) may be separated into five sequential phases: 1. suspected HIT, 2. acute HIT, 3. subacute HIT A, 4. subacute HIT B, and 5. remote HIT. Each phase confronts the clinician…

Descarga: Age dependency for coagulation parameters in paediatric populations Archivo: tromboembolia-venosa/infancia/th_2016-Age dependency for coagulation parameters in paediatric populations .pdf Understanding of developmental haemostasis is critical to ensure optimal prevention, diagnosis, and treatment of haemorrhagic and thrombotic diseases in children. As coagulation test results are known to be dependent on the reagents/analysers used, it is recommended…

Descarga: Cirrhosis as a risk factor for venous thrombosis Archivo: tromboembolia-venosa/tvp/th_2017-Cirrhosis as a risk factor for venous thrombosis.pdf Chronic and acute liver diseases have long been considered as the epitome of acquired bleeding disorders. Evidence in support of this included profoundly abnormal test results of routine diagnostic tests of haemostasis in combination with clinical bleeding…

Descarga: Clinical picture of heparin-induced thrombocytopenia (HIT) and its differentiation from non-HIT thrombocytopenia Archivo: tromboembolia-venosa/tvp/th_2016-Clinical picture of HITand its differentiation from non-HIT thrombocytopenia.pdf HIT is an acquired antibody-mediated disorder strongly associated with thrombosis, including microthrombosis secondary to disseminated intravascular dissemination (DIC). The clinical features of HIT are reviewed from the perspective of the 4Ts scoring…