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Coagulation factor XIII deficiency

Descarga: Coagulation factor XIII deficiency Archivo: ehh/haemo 2014-Coagulation factor XIII deficiency .pdf The plasma circulating zymogenic coagulation factor XIII (FXIII) is a protransglutaminase, which upon activation by thrombin and calcium cross-links preformed fibrin clots/fibrinolytic inhibitors making them mechanically stable and less susceptible to fibrino lysis. The zymogenic plasma FXIII molecule is a heterotetramer composed of…

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Recommendations for endoscopy in the patient on chronic anticoagulation: apply with care!

Descarga: Recommendations for endoscopy in the patient on chronic anticoagulation: apply with care! Archivo: guias/varias/PRECAUCIN CON LAS GUIAS.pdf With the escalating performance of colonoscopy in the United States over the past several years, there has been a consequent increase in the detection and the endoscopic removal of colonic polyps. Because colonic neoplasia is largely an…

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Perioperative management of patients who are receiving warfarin therapy: an evidence-based and practical approach

Descarga: Perioperative management of patients who are receiving warfarin therapy: an evidence-based and practical approach Archivo: guias/varias/Warfarina manejo perioperatorio guias.pdf The management of patients who are receiving anticoagulants and require surgery or an invasive procedure is a common clinical problem that, paradoxically, is both trivial and complex.1,2 It istrivial because stopping and resuming an anticoagulant…

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Apixaban

Descarga: Apixaban Archivo: tromboembolia-venosa/haemo 2012-apixaban.pdf Apixaban is a potent reversible inhibitor of the activated human coagulation factor X. This new oral anticoagulant has favourable pharmacokinetic and pharmocodynamic properties which include a concentration-dependent anticoagulant effect, good oral bioavailability, balanced elimination and excretion, infrequent drug or food interactions, and the lack of liver toxicity. Apixaban has already…

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