Categoría: Phoca Downloads Import

Descarga: Platelet-derived chemokines in atherosclerosis Archivo: tromboembolia-venosa/tvp/haemo_2015-Platelet-derived chemokines in atherosclerosis.pdf In atherosclerosis, activated platelets have been recently recognised not only to participate in thrombotic events but also to play an essential role in the development of atherosclerotic lesions. Upon their activation, platelets release several pro-inflammatory mediators including chemokines. Chemokines are key molecules in inflammation as…

Descarga: Newlocations of intravascular tissue factor Archivo: tromboembolia-venosa/tvp/haemo_2007-New locations of intravascular tissue factor .pdf Tissue factor (TF) is the major initiator of blood coagulation, and a mediator of inflammation, angiogenesis, and carcinogenesis. According to recent evidence, preformed TF and inducible expression of the protein is observed in several blood components. TF is apparently constitutively expressed…

Descarga: Oral anticoagulation with edoxaban Archivo: tromboembolia-venosa/haemo_2012-oral anticoagulation with edoxabanpdf.pdf Edoxaban (the former DU176b) an orally available direct factor Xa inhibitor has been engineered from DX-9065a, which was one of the first parenteral Xa inhibitors. Edoxaban has a time to peak plasma concentrations of 1–2 hours and a half-life of approximately 10 hours after multiple…